Yu, a girl who attempted suicide, was forced to stay in the acute psychiatric ward. Yu always kept to herself, but one day, she met a carefree girl, Kylie. As they wandered through sleepless nights, they became closer and closer. However, as the discharging day approaching, the atmosphere in the ward was turbulent. Faced with this "friend", Yu found herself in a difficult dilemma.

In 1926, Newt Scamander arrives at the Magical Congress of the United States of America with a magically expanded briefcase, which houses a number of dangerous creatures and their habitats. When the creatures escape from the briefcase, it sends the American wizarding authorities after Newt, and threatens to strain even further the state of magical and non-magical relations.