A toothpaste magnate's mischievous daughter, tired of her father's traditional ways of conducting business, joins forces with her father's rival and a crazy inventor. Together they create "Cocktail Toothpaste". The new concoction tastes like whiskey in the morning, a martini at suppertime, and champagne at night.

At the turn of the century Rose and ex-showbiz friend Molly get involved in selling steel. When they come unstuck with corsets they embark on the even more hazardous project of selling barbed wire to highly suspicious Texas cowboys.

Agatha Knabenshu arrives in a small town in Missouri to sell player pianos to the locals. She's fired after her disastrous sales attempts nearly destroy the town. The stranded saleslady becomes friendly with an equally bumbling inventor and moves in with his family. The two then try to sell his automatic milking machine, but things turn sour when their demonstration causes a stampede.