Dueling cat-and-mouse team Tom and Jerry hit the high seas on a hunt for buried treasure in this pirate adventure. The tale begins when crew member Tom sets sail with an infamous pirate and finds a treasure map along with stowaway Jerry. The furry swashbucklers race to a deserted island where X marks the spot, but along with battling each other, they must outwit ruthless buccaneers, angry monkeys and a giant octopus to strike it rich.

Tom subjects Jerry to his usual harassment; but the cat finds a new enemy, and the mouse finds a new friend, in the canary of the house.

Tom's in love again, and Jerry's devil conscience reminds him of times this has happened in the past (which, of course, we see, in the form of clips from earlier shorts), and how that's been nothing but trouble for Jerry.

Jerry runs into the Metropolitan Opera, trying to evade Tom.

Jasper is given an ultimatum by his master: break one more thing and you're out. Rodent Jerry does his best to make sure that his tormentor "gets the boot".

Tom and Jerry are in a bowling alley. Both spend a lot of time sliding on the well-polished lanes. Eventually, Jerry takes up residence among the pins and Tom tries to bowl him down.

Tom is playing with Jerry when a cute lady cat is delivered to Mammy for her to take care of. Tom is smitten at first sight.

Tom chases Jerry into a fish cannery; they get sealed into cans. Tom breaks out, but falls off a pier as the cans roll under him. A shark chases him out of the water; Tom drops an anchor on the shark. Meanwhile, Jerry has been hopping in his can; Tom opens it, and puts his finger in, which Jerry bites. Jerry tricks Tom into falling off the end of another pier, and right into the shark's path again. The shark manages to get Tom into a very precarious position, barely holding the jaws apart. Jerry takes pity, and dumps a shaker full of pepper into the shark, which ends up on the processing line and stuffed into a huge can. Tom is unrepentant, so Jerry tricks him with a fake shark fin.

2565 AD. Tom and Jerry are once again manipulating robot versions of themselves in space. Tom experiments with invisibility, a giant electromagnet, and explosives, with results from bad to disastrous.