A brilliant young college student named Griffin goes to his psychologist, Dr. Kemp, with a strange and frightening tale. A few days earlier, at the local university, he made an incredible breakthrough with his experiments involving invisibility. Not content to experiment on inanimate objects, he injected his invisibility serum into himself. At first, he reveled in achieving his life-long dream of becoming invisible ... but once he realized that the effects were permanent, his harmless excursions into eavesdropping and voyeurism turned murderous. Now, his enemies will suffer and even his friends are no longer safe as he hunts them down, one by one, within the confines of the deserted university campus.

When a lab experiment goes wrong, Benjamin Knight is left invisible while his scientist friends trying to find a formula that will restore his visibility to last the rest of his life.