Sara is a woman who was sexually abused and has been in pain ever since. Now, she has only one goal: to take revenge on every man who crosses his path, no matter what his intention is.

Some young women become fans of the figure of Sara, leader of the "Barrio Bitches", and closely follow her steps and upheavals.

Brenda sets up a white slave business after escaping from prison. Not a woman who has entered her business comes out alive.

Brenda and Sara are the most powerful women in Mexicali and they will do whatever it takes to maintain power no matter the consequences. A story full of action and eroticism that reflects today's society where the political class is involved with criminal groups to perpetuate themselves in power.

Brenda and Sara manage to escape from prison and return to the neighborhood to start a business and, with the help of El Sapo, open another elite whorehouse, which protects a very powerful person.