Giovanna Dei, a young cartoonist, works on the violent comic strip "Doctor Dark". Unfortunately, young women are being killed in the style of the comic strip character and she becomes the main suspect.

Dr. Génessier is riddled with guilt after an accident that he caused disfigures the face of his daughter, the once beautiful Christiane, who outsiders believe is dead. Dr. Génessier, along with accomplice and laboratory assistant Louise, kidnaps young women and brings them to the Génessier mansion. After rendering his victims unconscious, Dr. Génessier removes their faces and attempts to graft them on to Christiane's.