Seymour Krelborn is a nerdy orphan working at Mushnik's, a flower shop in urban Skid Row. He harbors a crush on fellow co-worker Audrey Fulquard, and is berated by Mr. Mushnik daily. One day Seymour finds a very mysterious unidentified plant which he calls Audrey II. The plant seems to have a craving for blood and soon begins to sing for his supper.

Seymour works in a skid row florist shop and is in love with his beautiful co-worker, Audrey. He creates a new plant that not only talks but cannot survive without human flesh and blood.

The fictional tale of the murderous 19th century barber (Ben Kinglsey) who sold his kills to a neighboring butcher (Joanna Lumley) for her renowned meat pies. A young innocent (Selina Boyack) and the dashing inspector (Campbell Scott) who tries to solve the murders are also thrown into the mix.

Barney Thomson, awkward, diffident, Glasgow barber, lives a life of desperate mediocrity and his uninteresting life is about to go from 0 to 60 in five seconds, as he enters the grotesque and comically absurd world of the serial killer.