Yuki (acted by Asami Kai), a senior high school student, is the leader of FIGHTING EXPRESS. Fujioka, who used to be a mercenary, is now a member of FIGHTING EXPRESS. One day a woman called Rei (acted by Kana Tsugihara) shows up to tell them she wants to join them. Rei is assigned the first mission after she has completed the hard training to join a member of FIGHTING EXPRESS with Fujioka. In Rei's first mission, there is a big conspiracy to threaten the continued existence of all humankind! Will Rei and Fujioka save the world?

They are "Behind-the-Scenes Delivery Specialists" who can deliver any kind of packages to anywhere in Japan. They run through dangerous areas and they fight with anyone standing in the way! Akane (acted by Yuka Kosaka), a would-be journalist, is chased by a shady black-suited group as she has an evidential document which can prove an assembly man's crime. So she runs to FIGHTING EXPRESS, which can deliver packages with special secret circumstances.

Endo, a member of FIGHTING EXPRESS, is well known as the strongest member. However, he is usually just a groupie hanging around an idol, Fuka (acted by Aya Kiguchi)... Finding out there's a devilish group stalking her, he draws fully upon the strength of the Akiba-kei Otaku's "pure love action" in order to save her!