Mysterious murders has been committed in four post-communist cities: Warsaw, Prague, Odesa, and Leipzig. The investigations are carried out by three absolutely different in many aspects criminal police officers. Independently of one another, they soon come to the conclusion that all four murders are connected. Now, to solve the crimes they have to work together.

Roy Tucker, a Vietnam war veteran with excellent shooting skills, is serving a long prison sentence when a mysterious visitor promises him that he will be released if he agrees to carry out a dangerous assignment.

After the death of his Nobel Prize-winning father, billionaire physicist Jerry Cornelius becomes embroiled in the search for the mysterious "Final Programme", developed by his father. The programme, a design for a perfect, self-replicating human being, is contained on microfilm. A group of scientists, led by the formidable Miss Brunner (who consumes her lovers), has sought Cornelius's help in obtaining it. After a chase across a war-torn Europe on the verge of anarchy, Brunner and Cornelius obtain the microfilm from Jerry's loathsome brother Frank. They proceed to an abandoned underground Nazi fortress in the Arctic to run the programme, with Jerry and Miss Brunner as the subjects.

The year is 1997, and World Peace seems to have come, with most classic weapons of mass destruction having been abandoned. However, orbiting the Earth there is the European/American space station FLORIDA ARKLAB, capable of controlling the weather at any location on the planet underneath. A civil project by nature, it might be abused as an offensive weapon, since it could deliver devastation to any potential adversary simply by creating natural disasters such as storms and floods. No wonder the space station soon becomes the central point in rising political tensions between East and West, next stop World War 3 (as indicated by the tagline "The end of our future has already begun"). We follow the main protagonist Billy Hayes, an astronaut aboard the station, as he wades through a plot of secrecy and sabotage trying to tell friend from foe in the process.

Having lost her place among the social elite, a widow remarries and starts a family.