While on a mission, American astronaut Captain Tony Nelson is forced to make an emergency landing that will forever change his life. On a deserted South Pacific island, Captain Nelson happens upon a bottle containing a beautiful two-thousand-year-old female genie named Jeannie. Rescuing her from the bottle nets Tony the requisite three wishes, and then some, when Jeannie pledges total devotion to her new "master".

Albert Einstein helps a young man who's in love with Einstein's niece to catch her attention by pretending temporarily to be a great physicist.