Tom invites Toots to an elegant dinner. However, he's made the mistake of trying to put Jerry to work, as a serving boy, a corkscrew, and other tasks. Jerry puts up with a little of this, but mostly gets revenge on Tom.

Spike is building the doghouse of his dreams. However, Tom chases Jerry through the chassis of the house and also pulls a board off it to attack the mouse with. When Jerry perches on Spike's head, even lying on top of his dream house does not stop it from being smashed. Tom bolts, but Spike stomps on his tail, then dusts himself off and wrenches the cat facing in his direction. He issues Tom an ultimatum: leave his dream house alone or suffer the consequences ("Wait a minute pussycat! Ever since I was a pup I've wanted a place of my own and I still want it! But if one thing happens to my little dreamhouse...there's goin' to be moider!").

Jerry is awakened from a nightmare by a knock on the door: someone has left a foundling in a walnut shell with a note, giving his name as Nibbles and saying he needs lots of milk. Fortunately, there's a dish handy, but it's next to Tom. Nibbles scurries out and dives off Tom's nose, then grabs a whisker for balance, waking Tom up. Jerry grabs him just in time and they hide under the milk. Tom laps up some milk and gets Nibbles; Jerry rescues him, and they run for the hole. Next, they try a very long straw; Tom catches them and sucks Nibbles through the straw. Much chasing follows, with a pause now and then for some milk. Tom traps Jerry in a milk bottle and chases Nibbles a while; he finally corners Nibbles and spanks him with a flyswatter. Jerry is so enraged he burst out of the milk bottle and lets out a ferocious roar; he grabs Tom by the tail and thoroughly pummels him, then stands over him as Tom feeds Nibbles milk.

Jerry runs into a dog pound (and right on top of a napping Spike) to escape a rather mangy-looking Tom. To avoid being ripped to shreds, Tom borrows the head of a nearby dog statue. This easily fools the dogs, but not Jerry, and Tom keeps losing his newfound head...

When Jerry invades Tom's new extra-deluxe, extra-large cat castle, Tom is determined to get Jerry out.

Jerry crashes a vase onto Tom's head, which gets Mammy to throw Tom out. Jerry at first revels in his freedom, but soon tires of this, and, under a flag of truce, hatches a plan with Tom.

Tom enjoys the role of top cat until an adorable red-and-white-haired kitten is brought into the house of a young blonde woman.

Jasper is given an ultimatum by his master: break one more thing and you're out. Rodent Jerry does his best to make sure that his tormentor "gets the boot".

Jerry mixes and drinks a high-acceleration potion which renders him so fast that he eats all of Tom's food before the bewildered cat can even see him.

Tom's advances on a young jive-talking girl cat get nowhere; nowhere, that is, until Tom gets a zoot suit. Armed with his miles of fabric and a new cool lingo, Tom still has to deal with the tricks of his nemesis, Jerry.

Secret agent Jerry-akin has to steal a giant refrigerator full of cheese, guarded by the evil Tom Thrush with a vast array of diabolical gadgets and traps. Of course, Jerry has a few tricks of his own.