In the fourth film of the Lone Wolf and Cub series, Ogami Itto is hired to kill a tattooed female assassin and battles Retsudo, head of the Yagyu clan, and his son Gunbei.

Japan's greatest jidaigeki star, Mifune Toshiro is Shogun's Advisor Okubo Hikozaemon who must be coaxed out of retirement to save Shogun Iemitsu from danger. The elderly Hikozaemon has been belittled of late and has seemingly lost the will to live, much less the desire to assert himself and make Iemitsu listen to reason. The plot thickens when a lovely young woman enters the picture. Can she change Hikozaemon's mind, and thus alter the path of Japanese history? No longer a young man, can Hikozaemon gain the shogun's ear, and succeed in warning him of the evil plot to overthrow him?