14-year-old Siddharta, wise beyond his age, has to deal every day with his heroin-addict mother Silvia and an absent father. One day, his four-year-old sister Domitilla accidentally pricks her finger on one of Silvia's used needles without her noticing. Seeking advice on the Internet, Siddharta is told to have her tested for hepatitis and AIDS. Thus he embarks on a odyssey of medical bureaucracy and both kind and uncaring adults.

The Facts of Life is an American sitcom that originally ran on the NBC television network from August 24, 1979, to May 7, 1988, making it the longest running sitcom of the 1980s. A spin-off of the sitcom Diff'rent Strokes, the series' premise focuses on Edna Garrett as she becomes a housemother at the fictional Eastland School, an all-female boarding school in Peekskill, New York.