Jake and Amir is an American comedy web series created by and starring CollegeHumor writers Jake Hurwitz and Amir Blumenfeld, and set in New York City. The two play humorous versions of themselves: Jake is usually depicted as a sensible "regular guy", and Amir as his annoying, obsessive and odd co-worker, the pair acting as a comic double act.

When a new CEO arrives at CollegeHumour, he makes Jake an offer he can't refuse: fire Amir and get a promotion, but Jake soon realizes life without Amir isn't as he'd hoped.