Three strangers share an obsession with true crime and suddenly find themselves wrapped up in one.

Although the title (which translates as "Murders in Chicago") promises a gangster story, this is more of a murder mystery that kicks off with the seemingly accidental death of a construction worker, followed shortly after by that of a noted publisher (an uneasy-looking Eduardo Fajardo). What follows is a very confusing story in which the police, a police coroner (José Campos) and a vagrant (Fernando Sánchez Polack) who witnessed Fajardo's death embark on separate inquests on what actually happened. Meanwhile, June (María Luisa Rubio), who works as a secretary for the publishing company, is under pressure by a blackmailer (Antonio Jiménez Escribano) who has pictures of her in the sack with the deceased publisher.

Joe Gavilan and his new partner K. C. Calden, are detectives on the beat in Tinseltown. Neither one of them really wants to be a cop, Gavilan moonlights as a real estate broker, and Calden is an aspiring actor moonlighting as a yoga instructor. When the two are assigned a big case they must work out whether they want to solve the case or follow their hearts.

Recently promoted and transferred to the homicide division, Inspector Jessica Shepard feels pressure to prove herself -- and what better way than by solving San Francisco's latest murder? However, as Shepard and her partner, Mike Delmarco, soon discover, the victim shared a romantic connection to her. As more of Shepard's ex-lovers turn up dead, her mind starts to become unstable, and she begins to wonder if she could be the very killer she's trying to track down.

Istanbul police commissioner Mehmet Özakin is in charge of serious crime, mainly murder investigations, mostly in the Turkish metropolis. A very modern Turk, he uses up to date Western methods, without prejudice, assisted by bachelor Mustafa Tombul. Even his private life is progressive, his wife Sevim being on the former imperial capital's university staff.

A young man goes up against a crooked town boss.

From his home in California, Simon's friend Jack is investigating the deaths of three prominent scientists. Shortly after making an important discovery, Jack is murdered, and the killer threatens to come after Simon.