When Jessica Drew was bitten by a poisonous spider as a child, her father saved her life by injecting her with an experimental "spider serum," which also granted her superhuman powers. As an adult, Jessica works as editor of Justice Magazine but when trouble arises, Jessica slips away to change into her secret identity of Spider-Woman.

Sherlock Holmes investigates a series of so-called "pajama suicides". He knows the female villain behind them is as cunning as Moriarty and as venomous as a spider. Based on "The Sign of Four" and the short stories "The Dying Detective", "The Final Problem", "The Speckled Band" and "The Adventure of the Devil's Foot".

The story of two radically different men thrown together in a Latin American prison cell. One is Valentin, a journalist being tortured for his political beliefs. The other is Molina, a gay window-dresser who fills their lonely nights by spinning romantic fantasies drawn from memories of old movies.