Barbary Coast is an American television series that aired on ABC. The pilot movie first aired on May 4, 1975 and the series itself premiered September 8, 1975; the last episode aired January 9, 1976. Barbary Coast was inspired by a similar 19th-century spy series, The Wild Wild West, and like the earlier program, Barbary Coast mixed the genres of Western and secret agent drama.

Mary Rutledge arrives from the east, finds her fiancé dead, and goes to work at the roulette wheel of Luis Chamalis' Bella Donna, a rowdy gambling house in San Francisco in the 1850s. She falls in love with miner Jim Carmichael and takes his gold dust at the wheel. She goes after him, Chamalis goes after her with intent to harm Carmichael.

After Bugs' giant gold nugget is stolen by Nasty Canasta, he tries to win it back at Canasta's San Francisco gambling hall.

Duke Fergus falls for Ann 'Flaxen' Tarry in the Barbary Coast in turn-of-the-century San Francisco. He loses money to crooked gambler Boss Tito Morell, goes home, learns to gamble, and returns. After he makes a fortune, he opens his own place with Flaxen as the entertainer; but the 1906 quake destroys his place.

Honest Plush Brannon is a con-man thrown out of the Barbary Coast in San Francisco in the 1880s and headed for the gold rush region of Nevada. He discovers a real mine which lead to several complications.

Panorama, Notorius 'Barbary Coast' after the 1906 San Francisco earthquake.

Wayne Adams is murdered in a Barbary Coast saloon and gambling hall in San Francisco in 1880, and his sister, Julie, enlists the aid of the district attorney, Michael Lodge, in gathering evidence in which to convict the owner of the gambling house of the crime. In order to do so, Julie poses as a dance-hall-girl, and soon finds herself in a dangerous situation.