In the 4th century B.C., a pagan shaman prophesies that Olympias, Queen of Macedonia, wife of King Phillip II will give birth to a baby who will grow up to destroy the world, and the baby named Alexander. Years later, Alexander with many successful campaigns unifies Persia and Macedonia, so great that it makes Aristotle worry that the world can be destroyed by Alexander's advance toward the East...

Prince Alexander, son of King Philip, and heir to the Macedonian empire, must fend off political saboteurs, assassins, and the jealousy of his own father to ascend to the position of king. Once there, he begins his quest to conquer all nations and become known as the Great King, though an ancient prophecy foretells that he will be the destroyer of the world and forever remembered as the Devil King.